Children

• Henry Prentiss (1749–1821)
• Joshua Prentiss (1744–1837)

Siblings

Half-siblings

• Nathan Prentice (1738–1769)
• Martha Prentice Ware (1724–1805)
• Caleb Prentiss (1722–1772)
• Elizabeth Prentice (1727–1769)
• Joshua Prentice (1719–1788)
• Hepzibah Prentice (1732–1811)
• Sarah Prentice (1741–1802)

Parents

• Henry Prentice (1693–1778)